Abstract: Let $G(s)=\sum\limits_{n=1}^{\infty} a_n \,n^{-s}$ be a Dirichlet series with coefficients bounded by $n^{\epsilon}$ for every $\epsilon>0$, and define $\beta_{k,G}$ to be the supremum of the real parts of zeros of combinations of $G$ and its $k$ first derivatives. In this talk, we give an asymptotic formula for the number $\beta_{k,G}$ and investigate in more detail the case of Dirichlet L-functions. We will also discuss an inverse-type problem for the Riemann-zeta function. In particular, we compute the degree of the largest derivative needed for such a combination to vanish at a given real number. For example, a combination that vanishes at $\beta=1,000,000$ will involve a derivative of order at least 2,178,301. This is joint work with A. Tamazyan and A. Zaharescu.